Soln for inj (SC) Moderate to severe plaque psoriasis in adults who failed to respond, or who have a contraindication to, or are intolerant to other systemic therapies including ciclosporin, MTX or PUVA. Moderate to severe plaque psoriasis in childn & adolescents ≥6 yr who are inadequately controlled by, or are intolerant to, other systemic therapies or phototherapies. As monotherapy or in combination w/ MTX for active psoriatic arthritis (PsA) in adults when the response to previous non-biological DMARD has been inadequate. Soln for inj (SC) & conc for soln for infusion (IV) Moderately to severely active Crohn's disease in adults who have had an inadequate response w/, lost response to, or were intolerant to either conventional therapy or TNFα antagonist or have medical contraindications to such therapies. Moderately to severely active ulcerative colitis in adults who have had an inadequate response w/, lost response to, or were intolerant to either conventional therapy or a biologic or have medical contraindications to such therapies.
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